A Trend of Plasma Renin Activity among Hypertensive Patients in Basra

Result: The study involved 144 patients. Eighty four (58.3%) patients were male and 60(41.7%) patients were female with an age range of 18-78 years and a mean age of 43.5 +/13 SD. Twenty four (16.7%) patients were less than 30 years old, 107(74.3%) patients were between 31-60 years and 13(9%) patients were more than 61 years. Twenty two (15.3%) patients were black and 122(84.7%) were white. Nine (6.3%) patients were obese, 59(41%) were overweight and 76(52.8%) were of normal weight. One hundred twenty four (86.7%) patients have no comorbidity, 7(4.9%) have diabetes, 4(2.8%) have CKD, 6(4.2%) have IHD and 2(1.4%) have stroke. Thirty nine (27.1%) patients were smoker and the rest were non smokers. In all age groups, the plasma renin was frequently high, 58.3 % in age group less than 30 years, 62.2% in age 31-60 years and 61.5% in over 61 years old but no statistical significant correlation (Pearson value = 0.931). In both genders, the plasma renin was frequently high 64.3% in male and 58.3% in female but there is no statistical significant correlation (Pearson value = 0.313). In all BMI groups, the plasma renin was frequently high 57.9% in normal weight, 67.8% in overweight and 55.6% in obese but there is no statistical significant correlation (Pearson value = 0.583). In regard to the race, 68.2% black patients have low plasma renin and 68% white patients have high plasma renin which was statistically significant (Pearson value = 0.000). The plasma renin was high both in hypertension less than 3 years (61.8%) and more than 3 years (61.9%) which was statistically non significant correlation (Pearson value = 0.988). In essential hypertension, 10.5% patients have low renin, 27.4% have normal renin and 62.1% have high renin. In comparison with secondary hypertension, there is no statistical significant correlation (Pearson value = 0.972). The plasma renin was high more frequently in systolic (63.6%), diastolic (58.6%) and systolic and diastolic (62.5%) hypertension but there is no statistical significant correlation (Pearson = 0.350). The plasma renin was high more frequently in smokers (61.5%) and non smokers (61.9%) but no statistical significant correlation (Pearson value = 0.360).